Brings back all these thoughts. I wrote this when I felt overwhelmed and it actually helped me. No change on my MRI scan will, temporarily at least, release a lot of these feelings.
Let's consider Orexin/hypocretin receptor signalling and how we may exploit this system for brain cancer management. As we can see in the diagrams below, orexin neutrons regulate various activities such as wakefulness, feeding, reward and thermogenesis. A ketogenic diet, normalisation of sleep/wake cycles, fasting, stimulation of thermogenic pathways and giving the brain fuels it thrives on could act as key strategies we can adopt to take advantage of the fact that orexin appears to have potential as a novel, highly-specific treatment for various localised and metastatic cancers. This is not quite as simple as it may sound as you can always have too much of a 'good' stressor or thing before it becomes 'bad'- eustress vs distress. We know of course that fat is a very efficient source of energy for the brain and ketone bodies are neuroprotective, the body energy level influences orexin neuronal activity to coordinate arousal and energy homeostasis. Management of chron...
This is finally in the news thanks to the Surviving Terminal Cancer film! http://www.telegraph.co.uk/lifestyle/wellbeing/healthadvice/11424747/The-professor-who-cured-his-cancer-with-a-cocktail-of-everyday-pills-and-20-years-on-remains-disease-free.html Please sign this petition so we can save more lives like this. We want to ensure innovative therapies get to brain tumour patients as quickly as possible. http://epetitions.direct.gov.uk/petitions/74463?dm_t=0,0,0,0,0
I've been thriving on my own version of a restricted ketogenic diet recently and learned a lot from attending this event last year so I thought I would share one of the videos (they have just become available online). :-) http://youtu.be/F3VQlWWDtiw The only difficulty I noticed personally when adapting to strict keto is that humans can have many more food intolerances than mice and many brain cancer patients are on anti convulsants so you have to play around with the diet (and often medication!) to find out what works for the individual. It is also easier to control a mouse's external environment. I noticed a number of migraine triggers relating to commonly recommended foods on the diet (eg. Cheese, double cream, dark chocolate, ground almonds, even coconut oil!). With most of these foods I am actually quite concerned that they are recommended in the first place but I won't go into that! Since I eliminated those foods and replaced them with different animal fats from gras...
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