Best Urdu Poetry Pics and Quotes Photos

I am in my 5th year since being diagnosed with incurable brain cancer. I should be happy right? Well, sometimes yes, sometimes no. Its complicated.  There have been many occasions that I didn't think I would make it this far. I feel incredibly fortunate, but even now I am still picking up all the pieces and coping with a 'new normal'. You learn to cope better with time, but its like grieving for a life lost. There is a new me that I don't recognise and have had to get to know, even if the essence of who I am stays the same, if you look closely behind the eyes can tell a different story. Sometimes people may just think I should leave it behind me and 'get on with it', but I can't, as, like it or not, its with me every day and I am scarred by it. The invisible disabilities,- the uncertainty,- and 'living in the moment' is how I live. day by day. I have to... and I have little choice.  Every day I experience some type of brain dysfunction that keeps me ...

These are the best blue light blocking glasses I have had and they don't look dorky. If you understand about the negative effects of artificial light at night you will understand how useful these can be to normalise natural melatonin secretion in the evenings. Endogenous melatonin produced by the pineal gland is one the most potent anti-cancer molecules known to man, as I have mentioned previously in this blog. The most noticeable benefit for me is improved seizure control after sunset. The effect of melatonin and sleep aids has been investigated for years as potential anti convulsive agents for good reason and the mechanisms of action go beyond improved sleep quality (although this is still HUGELY important for seizure control). Blue light blocking glasses from BLUblox-  https://www.blublox.com Melatonin is a very powerful antioxidant with numerous physiological functions. The interplay between clock genes and light entering the retina is an intricate, delicate process that regula...

At the moment I'm keeping an eye on trial results and emerging research of this relatively new medication (Erenumab) for episodic migraine to understand how it could have anti-cancer activity against angiogenesis in malignant brain tumours. Furness and Wookey, 2012 Erenumab is a human monoclonal antibody against the calcitonin gene-related peptide receptor (CGRP receptor) and its primary use is for the prevention of migraine. This simply means that it acts as an antagonist for the CGRP receptor. CGRP comprises of 37 amino acids and is produced in the peripheral and central neurons. The main function of this peptide is to transmit pain. Early studies in humans have shown that the drug could prevent migraines by up to 50% in phase 2 clinical trials (8) so wider spread use and future applications would be interesting to see. Long term safety requires further study as this is a relatively new drug. Research into CGPR receptor antagonists have been in development over the last few year...

'Mitochondrial ROS and H2O2 production may be a trigger, for driving mitochondrial oxidative stress, ultimately leading to increased mitochondrial oxidative metabolism in CSCs. Pharmaceuticals, chemical inhibitors, or natural products that we have identified to target CSCs, which interfere with a specific metabolic process or function, are shown in BLUE.' https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400535/

A few months ago (in March, in a previous post in my blog ), I theorised that stiripentol (the 'ketogenic diet pill') may be of use as an anti-cancer agent for brain cancer and perhaps others due to inhibition of Lactate Dehydrogenase activity. I think I have just found recent evidence that this theory may be valid. Stiripentol Stiripentol by Diatomit enhances beneficial effects of therapeutic ketosis for cancer management by inhibiting lactate dehydrogenase and offers neuroprotection and increased seizure threshold by enhancing central GABA neurotransmission. Here is an extra from the paper with reference to stiripentol and complimentary agents that could possibly offer a safe, synergistic therapeutic benefit. 'We have now identified a variety of clinically-approved drugs (stiripentol), natural products (caffein acid phenyl ester (CAPE), ascorbic acid, silibinin) and experimental pharmaceuticals (actinonin, FK866, 2-DG), that can be used to effectively inhibit cancer ste...

I am currently on day 5 of a 30 day experiment using myself as a human guinea pig to test these high potency probiotics from Visibiome. I first heard about this product from Dr. Rhonda Patrick and I trust her judgement. She stated how Visibiome contains 8 strains of live bacteria in concentrations of 450 billion bacteria per packet and I had this confirmed by the company that produces it.  Why is this so important? This is impressive as many probiotics only contain about 100 million bacteria (often dead as they should ideally be kept cold). I decided to investigate further and try these probiotics myself to see if I may benefit so I contacted the sister company based in the U.K. (Vivomaxx).  The gut micro biome. You are only 10% organically human. (9) Let's begin... I received them promptly in pill l form, placed in an ice packed package. I chose the capsules because the carbohydrate content is negligible so should not interfere with my ketogenic diet to manage my epilepsy. I ...