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Recently I have been combining exogenous ketones with BCAAs on my restricted protein ketogenic diet protocol to see how I react over time. Nutritional ketosis produces an increased ratio of plasma branched chain amino acids to aromatic amino acids which is one of its main proposed mechanisms of action for seizure control.  It has been suggested that the high ratio of plasma BCAAs/ARAAs could be useful for epileptics as it results in decreasing ARAAs- (ARAAs supposedly increase the excitability potential of the brain entering the central nervous system  ( Jirapinyo et al., 2004 )) . This shift resulting in a rise of BCAAs to ARAAs means that a state of ketosis will decrease the excitability potential of the brain and increase seizure threshold. The brain becomes more resilient to stress you could say and brain chemistry in general is more balanced as a result. I feel pretty good today but its just one day, one experiment, and the type I am taking also includes resveratrol and L...

Ok, so I haven't updated for a while which isn't ideal as I like to try and share what I've been up to lately. My shyness gets the better of me sometimes as well as that voice in my head that constantly says I'm never good enough and I don't deserve anything good to happen so why am I still doing well when others have tried their very best and they are no longer around. I know that I like to push things and think outside the box with every little thing that I try to be happy and to continue to keep the cancer beast away while controlling the epilepsy, but despite feeling very content I feel there is still something missing. Other days I feel deliriously happy for no reason, its just cool being alive and you realise what a gift that is, just feels like a selfish thought at times but keeps me sane. I've lost a lot of friends to brain cancer recently and it makes me feel numb because the sad fact is that I am getting used to hearing sad news. Personally I have coun...

In the third episode of the Beating Brain Cancer podcast we had the great pleasure of interviewing Dr. Angela Poff, Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida. Dr. Angela Poff Dr. Poff works in the Laboratory of Nutritional and Metabolic Medicine under the mentorship of Dr. Dominic D'Agostino. Her research focuses on the development and testing of non-toxic metabolic therapies for cancer and neurological disorders. Dr. Poff's research focuses primarily on vivo research using rodent models with metastatic cancer derived from human glioblastoma cell lines. The aim of her work is to observe the effects of nutritional ketosis, exogenous ketones and hyperbaric oxygen therapy and outline the underlying synergistic anti-cancer mechanisms behind these treatments. The audio recording of this interview is available here:   http://www.braincanceroptions.com/metabolic-therapeutics

I recently had the privilege of interviewing Dr. Wai Liu at St. George's University Hospital to talk about cannabinoids and cancer. More details of the interview can be found on my website here: http://www.braincanceroptions.com/news

Exercise was a huge seizure trigger for me since acquiring brain tumour related epilepsy. Over time my seizure threshold has improved thanks to a high DHA ketogenic diet. Yesterday I was able to run for the first time in 4 years. I managed 20 minutes p lus a light resistance workout. Today I ran 30 minutes without stopping at a decent pace.  I never thought this would be possible when I look back at where I've come, suffering those horrible grand mal seizures and now being on no medication with complete seizure control.  Never forget that our brains are made of fat and cholesterol. As I have written on several occasions, in and around malignant brain tumours we see dysregulated lipid composition when compared to healthy, disease free brains. This is often how neurosurgeons actually identify tumour tissue for resection, as described from the study below and from use of the iKnife, which identifies malignant tissue and can be combined with a form of photodynamic therap...

Despite exercise being a seizure trigger I enjoy my morning walks. Its at a pace which doesn't overstimulate my brain and I find it very calming. Walking allows me to reflect and to enjoy natural beauty. We have so many beautiful green spaces in this country and its a beautiful, sunny day today. The shorts will be on later and I'll do some sunbathing to top up the vitamin D. :)

Some new videos on my Youtube channel evaluating the efficacy of different forms and doses of aspirin for brain cancer management and as a potential anticonvulsant: I'm trying to get used to recording presentations using my computer. I'm not sure how to edit videos yet without hassle but I tried my best here. I hope people find this interesting, there are 3 videos in the series. Aspirin for brain cancer- part 1 Aspirin for brain cancer- part 2 Aspirin for brain cancer- part 3